Sugar acids and derivatives
Medchemexpress LLC Saikosaponin D | 20874-52-6 | MFCD09028095 | >=90.0% | 780.98 g/mol | C42H68O13 | 10 MG
Saikosaponin D is a triterpene saponin isolated from Bupleurum used in research for its anti-inflammatory, antibacterial, antitumor, and anti-allergic activities. It has been reported to inhibit selectin-mediated binding and downstream signaling pathways including STAT3 and NF-κB, and to activate estrogen receptor-β.
- Triterpene saponin with multiple reported bioactivities including anti-inflammatory and antitumor effects.
- Suitable for in vitro and preclinical research at small mg scale.
- Molecular formula C42H68O13; molecular weight 780.98 g/mol.
- CAS number 20874-52-6 for unambiguous identification.
- Purity reported ≥90% by HPLC in vendor reference.
Medchemexpress LLC OBI-992 drug-linker | 3039487-10-7 | 96.6% | 2173.46 | C106H162FN9O37 | 10 MG
OBI-992 drug-linker is an exatecan-based drug-linker conjugate designed for antibody-drug conjugate (ADC) synthesis. It links the TOP1 inhibitor exatecan to a cleavable linker to enable targeted delivery of the payload; preclinical studies report antitumor activity in mouse and PDX models. Supplied as a solid for research use, the product includes specified purity and storage recommendations for laboratory handling.
- Composed of exatecan linked to a cleavable linker.
- Demonstrated antitumor activity in preclinical models.
- High molecular weight compound suitable for ADC synthesis.
- Provided as a white to yellow solid.
- Purity 96.6%.
- Molecular weight 2173.46.
- Storage: sealed, away from moisture and light; in solvent -80°C for 6 months, -20°C for 1 month.
- Supplied in a 10 mg package for research use.
Medchemexpress LLC D-(+)-sorbose | 3615-56-3 | MFCD00151095 | 99.2% | 180.16 g/mol | C6H12O6 | 10 MG
D-(+)-Sorbose is the D-enantiomer of sorbose supplied for research use. It is a water-soluble monosaccharide sweetener used in metabolic and enzymatic studies and has been reported to inhibit disaccharidase activity and suppress postprandial blood glucose and insulin in animal models. Not for human consumption.
- High purity: 99.2%.
- Molecular weight: 180.16 g/mol.
- Chemical formula: C6H12O6.
- Soluble in water: 125 mg/mL (requires ultrasonic).
- Storage: store at 4°C and protect from light.
Medchemexpress LLC D-praziquanamine ((-)-praziquanamine) | 55375-92-3 | MFCD30491837 | 98.9% | 202.26 g/mol | C12H14N2O | 10 MG
D-Praziquanamine ((-)-praziquanamine) is the stereoisomer of L-praziquanamine, provided as a research reagent for use as an experimental control in biochemical and pharmacological studies.
- Isomer of L-praziquanamine, intended for use as an experimental control.
- CAS number 55375-92-3.
- Molecular formula C12H14N2O, molecular weight 202.26 g/mol.
- Typical purity ~98.9% (batch-specific; see certificate of analysis for details).
- Appearance: solid; also offered as a 10 mM solution in DMSO.
- Available in small sample sizes and milligram-scale quantities (for example, 10 mg).
eMolecules 1-O-Methyl-b-D-glucuronic acid sodium salt | 134253-42-2 | MFCD00083405 | 1g
Chem-Impex | 1-O-Methyl-b-D-glucuronic acid sodium salt | 1g | 603111949 | 20949 | | 134253-42-2 | MFCD00083405 | 230.148 | C7H11NaO7
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Medchemexpress LLC Lecithins, egg | 93685-90-6 | 25 MG
Lecithins, egg are pharmaceutical excipients, also known as pharmaceutical auxiliaries. These are chemical substances, other than active pharmaceutical ingredients, used in the pharmaceutical process. They are generally inactive ingredients in pharmaceutical preparations, improving stability, solubility, and processability. Additionally, they can influence the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
- Purity: 99.0%
- Appearance: Oil
- Color: Light yellow to brown
- Solubility: Soluble in ethanol (≥ 100 mg/mL)
Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 25 MG
BET bromodomain inhibitor 1 is an orally active and selective inhibitor of bromodomain and extra-terminal (BET) bromodomains. It demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest, inhibiting c-Myc expression, and upregulating p21 levels. Its primary applications involve research into acute myeloid leukemia, acute leukemia, and multiple myeloma.
- Orally active and selective BET bromodomain inhibitor.
- High affinity for BRD4 (IC50: 2.6 nM) and other BET bromodomains.
- Demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest.
- Effective against various cancer cell lines (Kasumi 1, MM1.S, MV4-11, and RS4-11).
- Excellent selectivity for BET bromodomain family over other bromodomains.
- Does not inhibit five cytochrome P450 enzymes.
- Exhibits strong antitumor activities in in-vivo models.
Medchemexpress LLC D-Thyroxine | 51-49-0 | 98.0% | C15H11I4NO4 | 25 MG
D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. It can inhibit goiter, promote metamorphosis of tadpoles, and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia. This product is intended for research applications only.
- Orally active thyroid hormone
- Inhibits the secretion of TSH
- Can inhibit goiter
- Promotes metamorphosis of tadpoles
- Influences cholesterol metabolism
- Used for the study of hypercholesterolemia
Medchemexpress LLC D-3263 hydrochloride | 1008763-54-9 | MFCD22665741 | 98.0% | 409.95 | C21H32ClN3O3 | 10 MG
D-3263 hydrochloride is an enteric-coated, orally bioavailable agonist of transient receptor potential melastatin member 8 (TRPM8). It binds and activates TRPM8, modulates calcium and sodium flux, and has been investigated for potential antineoplastic effects and modulation of androgen-related pathways.
- Orally bioavailable TRPM8 agonist suitable for in vivo studies.
- Enteric-coated formulation for improved gastrointestinal stability.
- High purity (98.0%) supports reproducible experimental results.
- Soluble in DMSO and formulatable for common in vivo vehicles.
- Stable when stored sealed at 4°C; solvent stability at -80°C for extended storage.
Medchemexpress LLC 4-Methylumbelliferyl β-D-galactopyranoside | 6160-78-7 | MFCD00036773 | 99.1% | 338.31 | 250 MG
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase. When cleaved, it produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer.
- Fluorescent substrate for β-galactosidase
- Produces a blue fluorescent coumarin fluorophore upon cleavage
- Fluorophore detectable by fluoroenzymeter or fluorometer
- Purity: 99.06%
- Molecular weight: 338.31
- Chemical formula: C16H18O8
- Appearance: Solid, white to off-white
- Emission (Em): 480; Excitation (Ex): 390
- Solubility: 41.67 mg/mL in DMSO
- Shipping: Room temperature
- Storage: -20°C (solid); -80°C (6 months) or -20°C (1 month) in solvent, protect from light
Medchemexpress LLC Tetrahydrouridine dihydrate | 18771-50-1 | MFCD00063468 | 99.8% | 284.26 g/mol | C9H20N2O8 | 10 MG
Tetrahydrouridine dihydrate is the dihydrated form of tetrahydrouridine, a potent competitive inhibitor of cytidine deaminase (CDA). Supplied as a white to off-white solid for research use, it is used to inhibit cytidine deamination, support studies of DNA/RNA synthesis pathways, and sensitize carcinoma cells to cytidine analog chemotherapeutics such as gemcitabine.
- Potent competitive inhibitor of cytidine deaminase (CDA).
- High purity (≈99.8%) suitable for research applications.
- Dihydrate form; molecular weight 284.26 g/mol.
- White to off-white solid, convenient for analytical and biological assays.
- Stable when stored as powder at -20°C (long-term storage).
- Available in small assay sizes for laboratory use.
Gold Biotechnology Inc NADH Beta Reduced Sodium Salt
Reduced -nicotinamide adenine dinucleotide (NADH) plays a major role in metabolism as a cofactor in redox reactions and as a mobile electron carrier NADH is a high energy compound that donates electrons to the electron transport chain to provide energy for ATP production by oxidative phosphorylation NADH is a required oxidizing cosubstrate in fermentation which regenerates NADH is fluorescent which provides for a relatively simple way to detect NADH in biological samples NADH is also used in enzyme cycling assays to detect relevant biological molecules in tissues